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Home >> Specialities >> Liver Transplant >> Liver Cirrhosis

Liver Cirrhosis

Cirrhosis of the liver is a stage of liver disease in which healthy liver tissue has been gradually replaced with scar tissue. This is a result of long-term, chronic hepatitis. Hepatitis is inflammation in your liver, which has many causes. When inflammation is ongoing, your liver attempts to repair itself by scarring. But too much scar tissue prevents your liver from working properly. The end stage is chronic liver failure.

Symptoms

Cirrhosis symptoms can be classified into two types: those associated with deteriorating liver function and those associated with portal hypertension. Symptoms of blocked bile flow, such as jaundice, are classic indicators of poor liver function. Symptoms of portal hypertension imply cirrhosis, particularly. Scar tissue in your liver compresses the portal vein. Cirrhosis symptoms associated with decreased liver function include:

  • Jaundice.
  • Pruritus.
  • Dark-colored pee and light-colored poop.
  • Digestive difficulties, especially with fats.
  • Small yellow bumps of fat deposits on your skin or eyelids.
  • Unexplained weight loss and muscle loss.
  • Hepatic encephalopathy.
  • Motor dysfunction.
  • Disruptions to your menstrual cycle.
  • Enlarged male breast tissue and shrunken testes in people with AMAB.

Causes

Cirrhosis is a progressive scarring process caused by chronic inflammation in the liver. Any chronic liver illness that produces chronic hepatitis can progress to cirrhosis. The most common causes are:

  • Alcohol-induced hepatitis. Chronic liver injury is the result of high alcohol consumption over time. While alcohol is the most well-known cause of liver cirrhosis, nonalcoholic causes are also prevalent.
  • Non-alcoholic steatohepatitis. This is chronic damage caused by increased fat buildup in your liver. It is linked to metabolic conditions such as elevated blood lipids, blood sugar, and blood pressure.
  • Chronic hepatitis C infection. Hepatitis C is a viral infection that usually progresses to chronicity. It is now treatable with antivirals, although many people are unaware they have it.
  • Chronic hepatitis B infection. Hepatitis B infection that has persisted over time. Hepatitis B is a viral infection that can become chronic in a small percentage of people. If it works, you'll have it for life. It is treatable, but not curable.

Diagnosis

A healthcare physician will first physically examine you for signs and symptoms of cirrhosis of the liver. They'll ask you when your symptoms started and whether they've altered over time. They will also inquire about your medical history, the drugs, herbs, or supplements you use, and your food and lifestyle. They will look for signs that may indicate a history of liver disease or injury. They will do additional medical tests to look for signs of liver cirrhosis. Tests can include:

  • Blood tests: A series of liver function tests can reveal indicators of liver disease and failure. These tests detect the levels of liver enzymes, proteins, and bilirubin in your bloodstream. Blood testing can also detect certain disorders or recognized negative effects, such as impaired blood coagulation.
  • Imaging tests: Imaging tests such as an abdominal ultrasound, CT scan, or MRI can reveal the size, shape, and texture of your liver. Elastography is a sort of imaging test that employs ultrasound or MRI technologies to detect liver stiffness or fibrosis.
  • Liver biopsy: A liver biopsy is a basic treatment that involves taking a small tissue sample from your liver and testing it in a lab. A healthcare provider can usually collect the sample using a hollow needle. While not always required, a liver biopsy can confirm cirrhosis and help establish the etiology.

Treatment

Cirrhosis causes persistent scarring in your liver that cannot be undone. While your liver has remarkable healing powers in general, cirrhosis is a stage of disease in which it no longer has enough healthy cells to heal itself. However, you may be able to reduce or prevent cirrhosis from growing further. This is determined by the reason, the extent to which it may be treated, and how well you respond to the treatment. Treatment for liver cirrhosis involves the following:

  • Managing the cause, if possible, to slow or mitigate the damage.
  • General dietary and lifestyle changes can help reduce liver stress.
  • Managing and screening for cirrhosis complications.
  • Liver transplantation is a last resort.

Prevention

You can stop liver disease from advancing to cirrhosis by treating it sooner. This is dependent on whether you are aware of it and whether you can take action to avoid it. Many people might not have symptoms at first, but a normal health checkup may assist in detecting them. This may provide you the opportunity to make significant adjustments or begin treatment.

Conclusion

Liver cirrhosis is a life-threatening disorder that requires early detection, lifestyle adjustments, and medical intervention to avoid complications. Individuals who are aware of the causes, symptoms, and treatment choices for liver disease can take proactive actions to safeguard their health. Adopting a healthy lifestyle and getting timely medical care can dramatically lessen the burden of liver cirrhosis, resulting in a higher quality of life and better results.

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